Preliminary Program

Topic Speaker
The Discovery of Insulin:

  • Historical Context at the University of Toronto
  • The Eli Lilly Insulin Story
  • The Novo Nordisk Insulin Story
Bernard Zinman
Ruth Gimeno
Peter Kurtzhals
The Discovery of Insulin, Diabetes, Science and Society-Perspective from the Academies

  • A Research Round Table Discussion to Focus on the Future Priorities and Strategies for Diabetes Research
Global Challenges in the Insulin Supply Change Jean Claude Mbanya
The Genetics of Insulin – From Cloning to Human Disease Graeme I. Bell
Basic science – Advances in Beta Cell and Islet Autoimmunity

  • Molecular insights into islet autoimmunity
  • Islet Inflammation and Type 1 Diabetes – New Perspectives
  • Development of Tolerance and Autoimmunity
  • Novel Strategies for Defeating Islet Autoimmunity
  • Therapeutic Approaches to Circumventing Autoimmunity

Alice Long
Decio L. Eizirik
Jayne Danska
Pere Santamaria
Kevan Herold

Clinical Science – Insulin Delivery, Special Situations

  • Insights from the T1D Exchange Experience
  • Barriers to Insulin Use in Adults
  • The Challenge of Insulin in Primary Care
  • Pump Therapy During Pregnancy
  • Insulin and Beyond in the Hospitalized Patient

David Maahs
Irl Hirsch
Stewart Harris
Denice Feig
Guillermo Umpierrez

Debate:

  • Whither the Future of Insulin Management in Type 2 Diabetes?
  • A Primary Role for Insulin Therapy in Type 2 Diabetes
John Buse
Hannele Yki-Järvinen
Mechanisms of Glucose Sensing Sabrina Diano
Cellular Consequences of Hypoglycemia Rory McCrimmon
Clinical Consequences of Hypoglycemia Stephanie Amiel
Minimizing Hypoglycemia in the Real World Chantal Mathieu
Defining the Underlying Defect in Insulin Action in Diabetes C. Ronald Kahn
Basic Science – Insulin Signaling in Health and Disease

  • How does Insulin Act on the Liver?
  • Insulin Action in Blood Vessels
  • Insulin Action in Muscle and Adipose Tissue
  • Insulin Action in the Kidney

Alan Cherrington
George King
Amira Klip
Richard Coward

Clinical Science

  • Comparative and Adjunctive Approaches to Insulin Delivery
  • New Closed Loop Insulin Systems
  • Bihormonal Glucose Management Systems
  • The Bleeding Edge: Open Source Algorithms, Research, and What’s Next in Do-It-Yourself Artificial Pancreas Systems

Bruce A. Perkins
Roman Hovorka
Steven J. Russell
Dana Lewis

Young Investigator Presentations TBD
Realizing the Promise of Stem Cell Therapy Douglas Melton
The Future of Smart Insulin Delivery Michael A. Weiss
The Present and Future of Pancreas and Islet Transplantation James Shapiro
Immune-based Therapies for Type 1 Diabetes Matthias von Herrath
Therapy of Type 1 Diabetes – The DCCT-EDIC Trials David Nathan
Preventing Diabetes in Children Carla Greenbaum